Korean J Thorac Cardiovasc Surg 2013 Apr; 46(02) 111-116
Heart Transplantation in the Elderly Patients: Midterm Results
Sang Yoon Yeom, M.D.1, Ho Young Hwang, M.D., Ph.D.1, Se-Jin Oh, M.D.1, Hyun-Jai Cho, M.D., Ph.D.2, Hae-Young Lee, M.D., Ph.D.2, Ki-Bong Kim, M.D., Ph.D.1
1Department of Thoracic and Cardiovascular Surgery, 2Cardiovascular Center and Cardiovascular Research Institute, Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine
Background: Heart transplantation in elderly patients has raised concerns because of co-morbidities and limited life expectancy in the era of donor shortage. We examined the outcomes after heart transplantation in elderly patients. Materials and Methods: From March 1994 to December 2011, 81 patients (male:female=64:17, 49.114.0 years) underwent heart transplantation. The outcomes after heart transplantation in the younger patients (60 years; group Y, n=60) were compared with those in the elderly patients (60 years; group O, n=21). The follow-up duration was 51.862.7 months. Results: Early mortality (30 days) occurred in 5.0% (3/60) and 4.8% (1/21) of groups Y and O, respectively (p0.999). There were no differences in overall survival between the two groups (p=0.201). Freedom from rejection was higher in group O than in group Y (p=0.026). Multivariable analysis revealed that age 60 years was not a significant risk factor for long-term survival; postoperative renal failure was the only significant risk factor for long-term survival (p=0.011). Conclusion: Early and mid-term results of heart transplantation in elderly patients were similar to those in younger patients.
Korean J Thorac Cardiovasc Surg 2013 Apr; 46(02) 111-116
Keyword : 1. Heart transplantation 2. Outcome assessment 3. Elderly